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Novel therapeutic avenues for the study of chronic liver disease and regeneration: The foundation of the Iberoamerican Consortium for the study of liver Cirrhosis.

Authors :
Sanz-Garcia C
Nevzorova YA
Martínez-Naves E
Cubero FJ
Hionides-Gutierrez A
Sañudo JR
Enrich C
Rentero C
Sancho-Bru P
Macías-Rodriguez RU
Ruiz-Margain A
Kershenobich-Stalnikowitz D
Vargas NR
Muñoz AE
Nakaya HI
Source :
Gastroenterologia y hepatologia [Gastroenterol Hepatol] 2023 Apr; Vol. 46 (4), pp. 322-328. Date of Electronic Publication: 2022 Jun 07.
Publication Year :
2023

Abstract

Unfortunately, there is a gap of understanding in the pathophysiology of chronic liver disease due to the lack of experimental models that exactly mimic the human disease. Additionally, the diagnosis of patients is very poor due to the lack of biomarkers than can detect the disease in early stages. Thus, it is of utmost interest the generation of a multidisciplinary consortium from different countries with a direct translation. The present reports the meeting of the 2021 Iberoamerican Consortium for the study of liver Cirrhosis, held online, in October 2021. The meeting, was focused on the recent advancements in the field of chronic liver disease and cirrhosis with a specific focus on cell pathobiology and liver regeneration, molecular and cellular targets involved in non-alcoholic hepatic steatohepatitis, alcoholic liver disease (ALD), both ALD and western diet, and end-stage liver cirrhosis and hepatocellular carcinoma. In addition, the meeting highlighted recent advances in targeted novel technology (-omics) and opening therapeutic avenues in this field of research.<br /> (Copyright © 2022 Elsevier España, S.L.U. All rights reserved.)

Details

Language :
English; Spanish; Castilian
ISSN :
0210-5705
Volume :
46
Issue :
4
Database :
MEDLINE
Journal :
Gastroenterologia y hepatologia
Publication Type :
Academic Journal
Accession number :
35688395
Full Text :
https://doi.org/10.1016/j.gastrohep.2022.05.012