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Analytical evaluation of thirty-two severe acute respiratory syndrome 2 lateral flow antigen tests demonstrates sensitivity remains with the SARS-CoV-2 Gamma lineage.
- Source :
-
Revista da Sociedade Brasileira de Medicina Tropical [Rev Soc Bras Med Trop] 2022 Jun 06; Vol. 55, pp. e0016. Date of Electronic Publication: 2022 Jun 06 (Print Publication: 2022). - Publication Year :
- 2022
-
Abstract
- Background: The emergence of variants of concern (VOCs) requires an ongoing assessment of the performance of antigen lateral flow tests (Ag-RDTs). The limit of detection (LOD) of 32 Ag-RDTs was evaluated using the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Gamma variant.<br />Methods: Ag-RDTs were performed according to the manufacturer's instructions with a clinical isolate of the Gamma variant.<br />Results: Twenty-eight of the 32 Ag-RDTs exceeded the World Health Organization criteria.<br />Conclusions: This comprehensive analytical evaluation of Ag-RDTs demonstrated that the test performance was maintained with Gamma VOC.
- Subjects :
- Humans
Sensitivity and Specificity
COVID-19 diagnosis
SARS-CoV-2
Subjects
Details
- Language :
- English
- ISSN :
- 1678-9849
- Volume :
- 55
- Database :
- MEDLINE
- Journal :
- Revista da Sociedade Brasileira de Medicina Tropical
- Publication Type :
- Academic Journal
- Accession number :
- 35674553
- Full Text :
- https://doi.org/10.1590/0037-8682-0016-2022