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A Comparative Analysis of Phenotypes Derived from Genes or Biomedical Literature in COVID-19.
- Source :
-
Studies in health technology and informatics [Stud Health Technol Inform] 2022 Jun 06; Vol. 290, pp. 1092-1093. - Publication Year :
- 2022
-
Abstract
- Since the emergence of SARS-CoV-2 in November 2019, there has been an exponential production of literature due to worldwide efforts to understand the interactions between the virus and the human body. Using an "in-house" developed script we retrieved gene annotations and identified phenotype enrichments. Human Phenotype Ontology terms were retrieved from the literature using the Onassis R package. This produced both disease-gene and disease-phenotype data as well as data for gene-phenotype interactions. Overall, we retrieved 181 human phenotypes that were identified by both approaches. Further in-depth analysis of these relationships could provide further insights in the molecular mechanisms related with the observed phenotypes, answers and hypotheses for key concepts within COVID-19 research.
- Subjects :
- Humans
Phenotype
SARS-CoV-2 genetics
COVID-19
Subjects
Details
- Language :
- English
- ISSN :
- 1879-8365
- Volume :
- 290
- Database :
- MEDLINE
- Journal :
- Studies in health technology and informatics
- Publication Type :
- Academic Journal
- Accession number :
- 35673221
- Full Text :
- https://doi.org/10.3233/SHTI220283