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ctDNA: Moving toward Clinical Utility.
- Source :
-
Cancer discovery [Cancer Discov] 2022 Aug 05; Vol. 12 (8), pp. OF4. - Publication Year :
- 2022
-
Abstract
- Findings from the phase II DYNAMIC study suggest that circulating tumor DNA analyses could help clinicians decide whether patients with stage II colon cancer require chemotherapy after standard surgery. Liquid biopsies could also shed light on the development of resistance to KRASG12C inhibition, paving the way for better treatment strategies.<br /> (©2022 American Association for Cancer Research.)
- Subjects :
- Biomarkers, Tumor analysis
Biomarkers, Tumor blood
Biomarkers, Tumor genetics
Drug Resistance, Neoplasm genetics
Humans
Liquid Biopsy
Mutation
Proto-Oncogene Proteins p21(ras) analysis
Proto-Oncogene Proteins p21(ras) genetics
Circulating Tumor DNA analysis
Circulating Tumor DNA blood
Circulating Tumor DNA genetics
Colonic Neoplasms blood
Colonic Neoplasms genetics
Colonic Neoplasms pathology
Colonic Neoplasms therapy
Subjects
Details
- Language :
- English
- ISSN :
- 2159-8290
- Volume :
- 12
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Cancer discovery
- Publication Type :
- Academic Journal
- Accession number :
- 35671334
- Full Text :
- https://doi.org/10.1158/2159-8290.CD-ND2022-0008