Does pharmacological treatment of depression in people with a primary brain tumour bring any benefits? A Cochrane Review summary with commentary.

Background: Persons with primary brain tumour can suffer from depression. Depression may hinder rehabilitation intervention leading to further deterioration of patient's health and functioning.
Objective: The Cochrane Review aimed to assess the effectiveness and adverse effects of pharmacological treatment of depression in people with a primary brain tumour.
Methods: A Cochrane Review by Beevers et al. was summarized with comments.
Results: The review did not find any eligible studies from the 2090 studies screened which included randomized controlled trials, cohort studies and case-control studies.
Conclusions: There is no high-quality evidence as to whether pharmacological treatments for depression in people with primary brain tumours are either effective or harmful.