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Handling parametric assumptions in principal causal effect estimation using Gaussian mixtures.

Authors :
Jo B
Source :
Statistics in medicine [Stat Med] 2022 Jul 20; Vol. 41 (16), pp. 3039-3056. Date of Electronic Publication: 2022 May 24.
Publication Year :
2022

Abstract

Given the latent stratum membership, principal stratification models with continuous outcomes naturally fit in the parametric estimation framework of Gaussian mixtures. However, with models that are not nonparametrically identified, relying on parametric mixture modeling has been mostly discouraged as a way of identifying principal effects. This study revisits this rather deserted use of parametric mixture modeling, which may open up various possibilities in principal stratification modeling. The main problem with using the parametric mixture modeling approach is that it is hard to assess the quality of principal effect estimates given its reliance on parametric conditions. As a way of assessing the estimation quality in this situation, this study proposes that we use parametric mixture modeling in two different ways, with and without the assurance of nonparametric identification. The key identifying assumption employed in this study is the moving exclusion restriction, a flexible version of the standard exclusion restriction assumption. This assumption is used as a temporary vehicle to help assess the quality of principal effect estimates obtained relying on parametric mixture modeling. The study presents promising results, showing the possibility of using parametric mixture modeling as an accessible tool for causal inference.<br /> (© 2022 John Wiley & Sons Ltd.)

Details

Language :
English
ISSN :
1097-0258
Volume :
41
Issue :
16
Database :
MEDLINE
Journal :
Statistics in medicine
Publication Type :
Academic Journal
Accession number :
35611438
Full Text :
https://doi.org/10.1002/sim.9401