A metal-organic framework@hydrogen-bond framework as a matrix for MALDI-TOF-MS analysis of small molecules.

Authors :: Yin SJ
Zheng GC
Yi X
Lv GP
Yang FQ
Source :: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2022 Jun 09; Vol. 58 (47), pp. 6701-6704. Date of Electronic Publication: 2022 Jun 09.
Publication Year :: 2022
Abstract: A novel MOF@HOF composite that can serve as a matrix for analysis of small molecules by MALDI-TOF-MS was fabricated through a simple solvothermal method. Taking falvonoids as an example, this composite/matrix presents high desorption/ionization efficiency, low background interference, high salt tolerance, and satisfactory signal reproducibility for MALDI-TOF-MS analysis.

Subjects :: Hydrogen
Reproducibility of Results
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization methods
Metal-Organic Frameworks

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