Back to Search
Start Over
New developments in skin-directed treatments of cutaneous T-cell lymphoma.
- Source :
-
Presse medicale (Paris, France : 1983) [Presse Med] 2022 Mar; Vol. 51 (1), pp. 104125. Date of Electronic Publication: 2022 May 10. - Publication Year :
- 2022
-
Abstract
- The therapeutic approach for mycosis fungoides, the most common type of primary cutaneous T-cell lymphoma, is based mainly on the stage of the disease, and skin-directed treatment is recommended by all international guidelines as the first-line of treatment for early-stage disease. Skin-directed treatments may be also given in combination with systemic therapies in early-stage mycosis fungoides patients recalcitrant to different types of skin-directed treatments, or in certain patients with high-risk features. Advanced-stage mycosis fungoides is treated mainly with systemic treatments, which may be combined with skin-directed treatments. Due to the rarity of mycosis fungoides, controlled clinical trials of the different skin-directed treatment modalities are almost non-existent, with a few exceptions, and therefore recommendations are largely based on cohort studies and expert opinion. This paper reviews the new developments in skin-directed treatments and provides an update on new studies of already well-known therapies, and an update on novel treatments.<br /> (Copyright © 2022.)
Details
- Language :
- English
- ISSN :
- 2213-0276
- Volume :
- 51
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Presse medicale (Paris, France : 1983)
- Publication Type :
- Academic Journal
- Accession number :
- 35562084
- Full Text :
- https://doi.org/10.1016/j.lpm.2022.104125