Back to Search
Start Over
Calcium carbonate nanowires: greener biosynthesis and their leishmanicidal activity.
- Source :
-
RSC advances [RSC Adv] 2020 Oct 14; Vol. 10 (62), pp. 38063-38068. Date of Electronic Publication: 2020 Oct 14 (Print Publication: 2020). - Publication Year :
- 2020
-
Abstract
- The synthesis of inorganic rod shape nanostructures is important in chromatography, dentistry, and medical applications such as bone implants, and drug and gene delivery systems. Herein, calcium carbonate (CaCO <subscript>3</subscript> ) nanowires were synthesized using a plant extract and the ensuing nanoparticles were characterized by XRD, FESEM, and HR-TEM. Then, the leishmanicidal effects of biogenic calcium carbonate nanowires were investigated against Leishmania major including the toxicity of varying concentrations of nanoparticles, and the percentage of viable and apoptotic cells based on flow cytometry analysis. Based on the results, the IC <subscript>50</subscript> of these polymorphs were calculated to be 800 μg mL <superscript>-1</superscript> . An ecofriendly, inexpensive, and novel biogenic method for the production of a new advanced inorganic nanostructure, CaCO <subscript>3</subscript> nanowires, is described without using hazardous chemicals; calcium carbonate nanowires maybe used as a smart drug carrier.<br />Competing Interests: The authors confirm that there are no competing interests.<br /> (This journal is © The Royal Society of Chemistry.)
Details
- Language :
- English
- ISSN :
- 2046-2069
- Volume :
- 10
- Issue :
- 62
- Database :
- MEDLINE
- Journal :
- RSC advances
- Publication Type :
- Academic Journal
- Accession number :
- 35548370
- Full Text :
- https://doi.org/10.1039/d0ra04503a