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Accuracy of a new electronic nose for prostate cancer diagnosis in urine samples.
- Source :
-
International journal of urology : official journal of the Japanese Urological Association [Int J Urol] 2022 Aug; Vol. 29 (8), pp. 890-896. Date of Electronic Publication: 2022 May 09. - Publication Year :
- 2022
-
Abstract
- Objective: To evaluate the accuracy of a new electronic nose to recognize prostate cancer in urine samples.<br />Methods: A blind, prospective study on consecutive patients was designed. Overall, 174 subjects were included in the study: 88 (50.6%) in prostate cancer group, and 86 (49.4%) in control group. Electronic nose performance for prostate cancer was assessed using sensitivity and specificity. The diagnostic accuracy of electronic nose was reported as area under the receiver operating characteristic curve.<br />Results: The electronic nose in the study population reached a sensitivity 85.2% (95% confidence interval 76.1-91.9; 13 false negatives out of 88), a specificity 79.1% (95% confidence interval 69.0-87.1; 18 false positives out of 86). The accuracy of the electronic nose represented as area under the receiver operating characteristic curve 0.821 (95% confidence interval 0.764-0.879).<br />Conclusions: The diagnostic accuracy of electronic nose for recognizing prostate cancer in urine samples is high, promising and susceptible to supplemental improvement. Additionally, further studies will be necessary to design a clinical trial to validate electronic nose application in diagnostic prostate cancer nomograms.<br /> (© 2022 The Authors. International Journal of Urology published by John Wiley & Sons Australia, Ltd on behalf of The Japanese Urological Association.)
Details
- Language :
- English
- ISSN :
- 1442-2042
- Volume :
- 29
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- International journal of urology : official journal of the Japanese Urological Association
- Publication Type :
- Academic Journal
- Accession number :
- 35534435
- Full Text :
- https://doi.org/10.1111/iju.14912