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Identity thieves: T cells steal CD20 from B cells but mark themselves for certain death.

Authors :
Sumida TS
O'Connor KC
Source :
Science immunology [Sci Immunol] 2022 May 06; Vol. 7 (71), pp. eabq7242. Date of Electronic Publication: 2022 May 06.
Publication Year :
2022

Abstract

T cells can acquire CD20 from B cells via trogocytosis, then contribute to autoimmune neurological disease while becoming targets for therapeutically effective B cell depletion.

Details

Language :
English
ISSN :
2470-9468
Volume :
7
Issue :
71
Database :
MEDLINE
Journal :
Science immunology
Publication Type :
Academic Journal
Accession number :
35522724
Full Text :
https://doi.org/10.1126/sciimmunol.abq7242