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State of the Art in Endoscopic Therapy for the Management of Gastroenteropancreatic Neuroendocrine Tumors.
- Source :
-
Current treatment options in oncology [Curr Treat Options Oncol] 2022 Jul; Vol. 23 (7), pp. 1014-1034. Date of Electronic Publication: 2022 May 05. - Publication Year :
- 2022
-
Abstract
- Opinion Statement: Gastroenteropancreatic neuroendocrine neoplasms (GEP NENs) comprise a heterogeneous group of slow growing tumors arising from the neuroendocrine cells of the gastrointestinal (GI) tract. Although they are considered relatively rare, their incidence is rising and it is believed that the more frequent use of endoscopy and imaging studies have at least in part contributed to the increased diagnosis especially of localized neoplasms. The management of these neoplasms should be guided by a multidisciplinary NEN team following appropriate staging investigations. Localized neoplasms of the GI tract may be suitable for endoscopic therapy, while patients with pancreatic NENs, unsuitable for surgery, should be considered for endoscopic ultrasound (EUS)-guided ablation. In this review, we discuss the evidence regarding endoscopic resection of luminal NENs and EUS-guided therapy of pancreatic NENs. The efficacy, safety, and other longer-term outcomes of these techniques are summarized. In conclusion, this review of endoscopic therapies for localized NENs may be a useful guide for NEN clinicians and endoscopists who are considering these therapeutic options for the management of focal GEP NENs.<br /> (© 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
- Subjects :
- Endoscopy
Humans
Gastrointestinal Neoplasms diagnosis
Gastrointestinal Neoplasms surgery
Intestinal Neoplasms diagnosis
Intestinal Neoplasms surgery
Neuroendocrine Tumors diagnosis
Neuroendocrine Tumors surgery
Pancreatic Neoplasms diagnosis
Pancreatic Neoplasms surgery
Stomach Neoplasms diagnosis
Stomach Neoplasms surgery
Subjects
Details
- Language :
- English
- ISSN :
- 1534-6277
- Volume :
- 23
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Current treatment options in oncology
- Publication Type :
- Academic Journal
- Accession number :
- 35511346
- Full Text :
- https://doi.org/10.1007/s11864-022-00986-w