Small Heat Shock Proteins in Retinal Diseases.

Authors :: Rajeswaren V
Wong JO
Yabroudi D
Nahomi RB
Rankenberg J
Nam MH
Nagaraj RH
Source :: Frontiers in molecular biosciences [Front Mol Biosci] 2022 Apr 11; Vol. 9, pp. 860375. Date of Electronic Publication: 2022 Apr 11 (Print Publication: 2022).
Publication Year :: 2022
Abstract: This review summarizes the latest findings on small heat shock proteins (sHsps) in three major retinal diseases: glaucoma, diabetic retinopathy, and age-related macular degeneration. A general description of the structure and major cellular functions of sHsps is provided in the introductory remarks. Their role in specific retinal diseases, highlighting their regulation, role in pathogenesis, and possible use as therapeutics, is discussed.<br />Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.<br /> (Copyright © 2022 Rajeswaren, Wong, Yabroudi, Nahomi, Rankenberg, Nam and Nagaraj.)