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Effects of microRNAs and long non-coding RNAs on chemotherapy response in glioma.
- Source :
-
Epigenomics [Epigenomics] 2022 May; Vol. 14 (9), pp. 549-563. Date of Electronic Publication: 2022 Apr 27. - Publication Year :
- 2022
-
Abstract
- Glioma is the most prevalent invasive primary tumor of the central nervous system. Glioma cells can spread and infiltrate into normal surrounding brain tissues. Despite the standard use of chemotherapy and radiotherapy after surgery in glioma patients, treatment resistance is still a problem, as the underlying mechanisms are still not fully understood. Non-coding RNAs are widely involved in tumor progression and treatment resistance mechanisms. In the present review, we discuss the pathways by which microRNAs and long non-coding RNAs can affect resistance to chemotherapy and radiotherapy, as well as offer potential therapeutic options for future glioma treatment.
Details
- Language :
- English
- ISSN :
- 1750-192X
- Volume :
- 14
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Epigenomics
- Publication Type :
- Academic Journal
- Accession number :
- 35473299
- Full Text :
- https://doi.org/10.2217/epi-2021-0439