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Retroperitoneal abscess and splenitis with Clostridium spp. in a dog.
- Source :
-
Veterinary clinical pathology [Vet Clin Pathol] 2022 Dec; Vol. 51 (4), pp. 560-564. Date of Electronic Publication: 2022 Apr 15. - Publication Year :
- 2022
-
Abstract
- An 11-year-old spayed female Basset Hound was presented to the Colorado State University Veterinary Teaching Hospital for evaluation of a 7-week history of intermittent collapse, waxing and waning lethargy, and hyporexia. Abdominal ultrasound revealed a 6-mm hypoechoic splenic nodule that, on cytologic evaluation, revealed marked neutrophilic inflammation with intracellular and extracellular bacterial rods frequently producing oval subterminal to terminal endospores, suggestive of Clostridium. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF) performed on bacteria isolated from this nodule initially identified a Clostridium species, which was eventually confirmed with 16 s rDNA sequencing. Computed tomography (CT) and exploratory laparotomy subsequently identified a 2.5-cm diameter tubular structure beginning at the caudal aspect of the right kidney and coursing caudally containing gas and fluid, consistent with a retroperitoneal abscess, which was resected and also cultured Clostridium spp. The dog was discharged 3 days postoperatively and was alive at the time of writing, 7 months after discharge. This case highlights a previously unrecognized bacterial agent in a retroperitoneal abscess. The use of cytologic evaluation yielded a diagnosis of endospore-forming bacteria suggestive of Clostridium sooner than culture and histopathology, which allowed for adjustment in the antibiotic protocol.<br /> (© 2022 American Society for Veterinary Clinical Pathology.)
- Subjects :
- Dogs
Female
Animals
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization veterinary
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization methods
Abscess diagnosis
Abscess veterinary
Hospitals, Animal
Hospitals, Teaching
Clostridium genetics
Splenic Diseases diagnosis
Splenic Diseases veterinary
Dog Diseases diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 1939-165X
- Volume :
- 51
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Veterinary clinical pathology
- Publication Type :
- Report
- Accession number :
- 35428981
- Full Text :
- https://doi.org/10.1111/vcp.13112