PI3K-α/mTOR/BRD4 inhibitor alone or in combination with other anti-virals blocks replication of SARS-CoV-2 and its variants of concern including Delta and Omicron.

Subjects

Subjects :

Antiviral Agents pharmacology
Cell Cycle Proteins antagonists & inhibitors
Humans
Phosphatidylinositol 3-Kinases
TOR Serine-Threonine Kinases antagonists & inhibitors
Transcription Factors antagonists & inhibitors
Virus Replication drug effects
Phosphoinositide-3 Kinase Inhibitors pharmacology
SARS-CoV-2 drug effects
COVID-19 Drug Treatment

Details

Language :

English

ISSN :

2001-1326

Volume :

12

Issue :

4

Database :

MEDLINE

Journal :

Clinical and translational medicine

Publication Type :

Editorial & Opinion

Accession number :

35390226

Full Text :

https://doi.org/10.1002/ctm2.806