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Association of Primary Open-angle Glaucoma With Tinnitus: A Nationwide Population-Based Study.

Authors :
Kuang TM
Xirasagar S
Cheng YF
Kuo NW
Lin HC
Source :
Journal of glaucoma [J Glaucoma] 2022 Apr 01; Vol. 31 (4), pp. 224-227.
Publication Year :
2022

Abstract

Prcis: This study aims to investigate the association between primary open-angle glaucoma (POAG) and tinnitus. We found that tinnitus was significantly associated with preexisting POAG [adjusted odds ratio (OR)=1.298].<br />Purpose: The purpose of this study was to investigate the association between POAG and tinnitus using nationwide population-based data from Taiwan.<br />Methods: Data for this case-control study were retrieved from the Taiwan National Health Insurance Research Database for all 542,682 patients with a first-time diagnosis of tinnitus (cases), and 1,628,046 propensity score-matched controls from Taiwan's National Health Insurance system. We performed multiple logistic regression analysis to estimate the odds (ORs) of prior POAG among cases versus controls.<br />Results: Of total 2,170,728 study patients, 85,257 (3.93%) had POAG before the index date of tinnitus, 25,496 (4.70%) among cases and 59,761 (3.67%) among controls (P<0.001). Multiple logistic regression analysis showed a significant association between prior POAG and tinnitus (OR=1.298, 95% confidence interval: 1.278-1.318) after adjusting for age, sex, monthly income, geographic location and residential urbanization level, hyperlipidemia, diabetes, obesity, anemia, rheumatoid arthritis, alcohol abuse, nicotine dependence, anxiety disorder, depressive disorder, and hypertension.<br />Conclusions: Patients with POAG have a higher risk of tinnitus compared with those without the disease. Ophthalmologists should be aware of this association and further studies are needed to understand underlying mechanisms.<br />Competing Interests: Disclosure: The authors declare no conflict of interest.<br /> (Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.)

Details

Language :
English
ISSN :
1536-481X
Volume :
31
Issue :
4
Database :
MEDLINE
Journal :
Journal of glaucoma
Publication Type :
Academic Journal
Accession number :
35353782
Full Text :
https://doi.org/10.1097/IJG.0000000000002001