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Acute kidney injury due to intravenous detergent poisoning: A case report.

Authors :
Park S
Ryu HS
Lee JK
Park SS
Kwon SJ
Hwang WM
Yun SR
Park MH
Park Y
Source :
World journal of clinical cases [World J Clin Cases] 2022 Feb 26; Vol. 10 (6), pp. 2036-2044.
Publication Year :
2022

Abstract

Background: Detergent poisoning mostly occurs through oral ingestion (> 85%), ocular exposure (< 15%), or dermal exposure (< 8%). Reports of detergent poisoning through an intravenous injection are extremely rare. In addition, there are very few cases of renal toxicity directly caused by detergents. Here, we report a unique case of acute kidney injury caused by detergent poisoning through an accidental intravenous injection.<br />Case Summary: A 61-year-old man was intravenously injected with 20 mL of detergent by another patient in the same room of a local hospital. The surfactant and calcium carbonate accounted for the largest proportion of the detergent. The patient complained of vascular pain, chest discomfort, and nausea, and was transferred to our institution. After hospitalization, the patient's serum creatinine level increased to 5.42 mg/dL, and his daily urine output decreased to approximately 300 mL. Renal biopsy findings noted that the glomeruli were relatively intact; however, diffuse acute tubular injury was observed. Generalized edema was also noted, and the patient underwent a total of four hemodiafiltration sessions. Afterward, the patient's urine output gradually increased whereas the serum creatinine level decreased. The patient was discharged in a stable status without any sequelae.<br />Conclusion: Detergents appear to directly cause renal tubular injury by systemic absorption. In treating a patient with detergent poisoning, physicians should be aware that the renal function may also deteriorate. In addition, timely renal replacement therapy may help improve the patient's prognosis.<br />Competing Interests: Conflict-of-interest statement: The authors declare that they have no conflict of interest.<br /> (©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.)

Details

Language :
English
ISSN :
2307-8960
Volume :
10
Issue :
6
Database :
MEDLINE
Journal :
World journal of clinical cases
Publication Type :
Academic Journal
Accession number :
35317142
Full Text :
https://doi.org/10.12998/wjcc.v10.i6.2036