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Severity of COVID-19 Infection Using Chest Computed Tomography Severity Score Index Among Vaccinated and Unvaccinated COVID-19-Positive Healthcare Workers: An Analytical Cross-Sectional Study.

Severity of COVID-19 Infection Using Chest Computed Tomography Severity Score Index Among Vaccinated and Unvaccinated COVID-19-Positive Healthcare Workers: An Analytical Cross-Sectional Study.

Authors :
Ravindra Naik B
Anil Kumar S
Rachegowda N
Yashas Ullas L
Revanth RB
Venkata Sai Aluru NR
Source :
Cureus [Cureus] 2022 Feb 10; Vol. 14 (2), pp. e22087. Date of Electronic Publication: 2022 Feb 10 (Print Publication: 2022).
Publication Year :
2022

Abstract

Introduction: Coronavirus disease 2019 (COVID-19) vaccines protect against severe illness. However, data on post-vaccination COVID-19 breakthrough infections are limited.<br />Methods: An analytical cross-sectional study was conducted from May 2021 to July 2021 among 2043 COVID-19-positive healthcare workers who were divided into a vaccinated group (n=1010) and an unvaccinated group (n=1033). A pre-tested questionnaire was circulated among the healthcare workers using Google Forms. Chest computed tomography (CT) severity score was the primary outcome variable analyzed using coGuide.<br />Results: The average age of the study population was less than 45 years in both groups (43.05 ± 13.02 years). Most respondents (62%) were males. Hypertension (39%) and diabetes (33%) were the most common underlying diseases. Significant differences in age and cardiac disease were observed between the two groups ( p  = 0.07 and  p  <0.001, respectively). However, the difference was insignificant ( p  >0.05) for gender, hypertension, and diabetes. Most unvaccinated respondents had an increased CT severity score, and the difference between the studies groups was significant ( p  <0.001). Of the 1,010 vaccinated individuals, 382 (37.82%) received the only first vaccination dose, and 628 (62.18%) received both doses. The CT severity score decreased after receiving both vaccination doses, and the difference between CT severity score and vaccination status was significant ( p  <0.001).<br />Conclusion: COVID-19 was mild in the vaccinated group. Chest CT severity score index can be considered an efficient tool in predicting prognosis and monitoring disease in patients with COVID-19 in India.<br />Competing Interests: The authors have declared that no competing interests exist.<br /> (Copyright © 2022, Ravindra Naik et al.)

Details

Language :
English
ISSN :
2168-8184
Volume :
14
Issue :
2
Database :
MEDLINE
Journal :
Cureus
Publication Type :
Academic Journal
Accession number :
35295366
Full Text :
https://doi.org/10.7759/cureus.22087