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Efficacy of EPA-registered disinfectants against two human norovirus surrogates and Clostridioides difficile endospores.
- Source :
-
Journal of applied microbiology [J Appl Microbiol] 2022 Jun; Vol. 132 (6), pp. 4289-4299. Date of Electronic Publication: 2022 Mar 17. - Publication Year :
- 2022
-
Abstract
- Aims: To determine the efficacy of a panel of nine EPA-registered disinfectants against two human norovirus (HuNoV) surrogates (feline calicivirus [FCV] and Tulane virus [TuV]) and Clostridioides difficile endospores.<br />Methods and Results: Nine EPA-registered products, five of which contained H <subscript>2</subscript> O <subscript>2</subscript> as active ingredient, were tested against infectious FCV, TuV and C. difficile endospores using two ASTM methods, a suspension and carrier test. Efficacy claims against FCV were confirmed for 8 of 9 products. The most efficacious product containing H <subscript>2</subscript> O <subscript>2</subscript> as ingredient achieved a >5.1 log reduction of FCV and >3.1 log reduction of TuV after 5 min, and >6.0 log reduction of C. difficile endospores after 10 min. Of the five products containing H <subscript>2</subscript> O <subscript>2</subscript> , no strong correlation (R <superscript>2</superscript>  = 0.25, p = 0.03) was observed between disinfection efficacy and H <subscript>2</subscript> O <subscript>2</subscript> concentration. Addition of 0.025% ferrous sulphate to 1% H <subscript>2</subscript> O <subscript>2</subscript> solution improved efficacy against FCV, TuV and C. difficile.<br />Conclusion: Disinfectants containing H <subscript>2</subscript> O <subscript>2</subscript> are the most efficacious disinfection products against FCV, TuV and C. difficile endospores. Product formulation, rather than the concentration of H <subscript>2</subscript> O <subscript>2</subscript> in a product, impacts the efficacy of a disinfection product.<br />Significance and Impact of Study: H <subscript>2</subscript> O <subscript>2</subscript> -based disinfectants are efficacious against surrogate viruses for HuNoV and C. difficile endospores.<br /> (© 2022 Society for Applied Microbiology.)
Details
- Language :
- English
- ISSN :
- 1365-2672
- Volume :
- 132
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Journal of applied microbiology
- Publication Type :
- Academic Journal
- Accession number :
- 35279925
- Full Text :
- https://doi.org/10.1111/jam.15524