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Biotechnological Innovations from Ocean: Transpiring Role of Marine Drugs in Management of Chronic Disorders.

Authors :
Bhatia S
Makkar R
Behl T
Sehgal A
Singh S
Rachamalla M
Mani V
Iqbal MS
Bungau SG
Source :
Molecules (Basel, Switzerland) [Molecules] 2022 Feb 24; Vol. 27 (5). Date of Electronic Publication: 2022 Feb 24.
Publication Year :
2022

Abstract

Marine drugs are abundant in number, comprise of a diverse range of structures with corresponding mechanisms of action, and hold promise for the discovery of new and better treatment approaches for the management of several chronic diseases. There are huge reserves of natural marine biological compounds, as 70 percent of the Earth is covered with oceans, indicating a diversity of chemical entities on the planet. The marine ecosystems are a rich source of bioactive products and have been explored for lead drug molecules that have proven to be novel therapeutic targets. Over the last 70 years, many structurally diverse drug products and their secondary metabolites have been isolated from marine sources. The drugs obtained from marine sources have displayed an exceptional potential in the management of a wide array of diseases, ranging from acute to chronic conditions. A beneficial role of marine drugs in human health has been recently proposed. The current review highlights various marine drugs and their compounds and role in the management of chronic diseases such as cancer, diabetes, neurodegenerative diseases, and cardiovascular disorders, which has led to the development of new drug treatment approaches.

Details

Language :
English
ISSN :
1420-3049
Volume :
27
Issue :
5
Database :
MEDLINE
Journal :
Molecules (Basel, Switzerland)
Publication Type :
Academic Journal
Accession number :
35268639
Full Text :
https://doi.org/10.3390/molecules27051539