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[Successful child delivery in treatment-free remission of chronic myeloid leukemia after discontinuation of dasatinib].

Authors :
Hirose N
Fujisawa S
Sakuma T
Matsumura A
Miyashita K
Nakajima Y
Nakajima H
Source :
[Rinsho ketsueki] The Japanese journal of clinical hematology [Rinsho Ketsueki] 2022; Vol. 63 (2), pp. 114-116.
Publication Year :
2022

Abstract

A 21-year-old woman was diagnosed with chronic myeloid leukemia in March 2014. The patient and her family did not wish to freeze eggs before dasatinib initiation. After 66 months of oral dasatinib administration and 40 months of MR4.5 maintenance, the patient requested to discontinue dasatinib due to a desire to conceive. MR4.5 maintenance was continued, and she achieved spontaneous pregnancy 6 months after dasatinib discontinuation. The patient gave birth to a normal baby 13 months later and was on MR4.5 maintenance 21 months after dasatinib discontinuation.

Details

Language :
Japanese
ISSN :
0485-1439
Volume :
63
Issue :
2
Database :
MEDLINE
Journal :
[Rinsho ketsueki] The Japanese journal of clinical hematology
Publication Type :
Academic Journal
Accession number :
35264501
Full Text :
https://doi.org/10.11406/rinketsu.63.114