Peritumoral Immunoglobulin M Lambda Light Chain Amyloidosis in a Patient With Advanced Follicular Lymphoma.

Authors :: Shah K
Kollimuttathuillam SV
Bethel N
Shaaban H
Source :: Cureus [Cureus] 2022 Jan 30; Vol. 14 (1), pp. e21738. Date of Electronic Publication: 2022 Jan 30 (Print Publication: 2022).
Publication Year :: 2022
Abstract: Peritumoral light chain (AL) amyloidosis secondary to lymphoid malignancies is a rare but well-described entity. Peritumoral deposition of amyloid without systemic amyloidosis has been described in mucosa-associated lymphoid tissue (MALT) lymphomas; however, there are no reported cases of follicular lymphoma with localized peritumoral AL amyloidosis without systemic involvement of amyloidosis. We present a rare case of a patient with advanced follicular lymphoma with peritumoral lymph node IgM lambda light chain amyloidosis without an underlying monoclonal gammopathy or plasma cell dyscrasia.<br />Competing Interests: The authors have declared that no competing interests exist.<br /> (Copyright © 2022, Shah et al.)

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