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Toxicity of microplastics and copper, alone or combined, in blackspot seabream (Pagellus bogaraveo) larvae.
- Source :
-
Environmental toxicology and pharmacology [Environ Toxicol Pharmacol] 2022 Apr; Vol. 91, pp. 103835. Date of Electronic Publication: 2022 Feb 25. - Publication Year :
- 2022
-
Abstract
- Plastics pose serious risks for fish productivity and a potential constraint for food security. Newly hatched blackspot seabream larvae were exposed to microplastics (MPs), copper (Cu, 10-810 µg/L) and their mixtures (Cu+MPs), during 3 and 9 days. Biochemical biomarkers and the expression of antioxidant and neurotoxicity-related genes were evaluated. In the 3-day exposure, catalase and glutathione-S-transferase activities decreased in MPs, Cu and Cu+MPs groups, followed by an increase of lipid peroxidation in the Cu270 and Cu270 +MPs exposed larvae. In the 9-day exposure, ROS levels increased in MPs and Cu30 groups, but no significant oxidative damage was observed, suggesting that the antioxidant system overcome the induced oxidative stress. However, the acetylcholinesterase transcript was downregulated in MPs, Cu and Cu10+MPs groups, indicating that MPs effects in cholinergic neurotransmission may arise after longer exposures. Overall, MPs and Cu can reduce survival, induce oxidative stress, lipid peroxidation, neurotoxicity, and impact negatively fish larvae fitness.<br /> (Copyright © 2022 Elsevier B.V. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1872-7077
- Volume :
- 91
- Database :
- MEDLINE
- Journal :
- Environmental toxicology and pharmacology
- Publication Type :
- Academic Journal
- Accession number :
- 35227885
- Full Text :
- https://doi.org/10.1016/j.etap.2022.103835