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Highly Advanced Colorectal Liver Metastases Successfully Treated With Fluorouracil Plus Leucovorin Monotherapy and Microwave Ablation.
- Source :
-
Anticancer research [Anticancer Res] 2022 Mar; Vol. 42 (3), pp. 1645-1651. - Publication Year :
- 2022
-
Abstract
- Background: Fluorouracil plus leucovorin (5-FU/LV) is a less toxic but mild chemotherapy.<br />Case Report: A 63-year-old male patient with rectal cancer and multiple colorectal liver metastases (CRLM, total volume of 1,826 ml) was hospitalized. He had several poor prognostic factors, including elevated levels of tumor markers, with carcinoembryonic antigen and carbohydrate antigen 19-9 levels of 17,119 ng/ml and 7,617 U/ml, respectively. Additionally, the patient had a low body mass index, poor performance status, and a history of apparent weight loss. After capecitabine and oxaliplatin for four cycles, 5-FU/LV has been lasting for nine months. Interestingly, tumor marker levels returned close to normal limits, and the total CRLM volume decreased to 154 ml without any enhancements. The patient's general condition clearly improved after a year of chemotherapy.<br />Conclusion: Chemotherapy with 5-FU/LV and percutaneous microwave ablation is beneficial to achieve tumor control in patients with highly advanced liver-only CRLM and poor general condition.<br /> (Copyright © 2022 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.)
- Subjects :
- Adenocarcinoma diagnostic imaging
Adenocarcinoma secondary
Chemotherapy, Adjuvant
Humans
Liver Neoplasms diagnostic imaging
Liver Neoplasms secondary
Male
Middle Aged
Treatment Outcome
Ablation Techniques
Adenocarcinoma therapy
Antineoplastic Combined Chemotherapy Protocols therapeutic use
Colorectal Neoplasms pathology
Fluorouracil therapeutic use
Leucovorin therapeutic use
Liver Neoplasms therapy
Microwaves therapeutic use
Neoadjuvant Therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1791-7530
- Volume :
- 42
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Anticancer research
- Publication Type :
- Report
- Accession number :
- 35220264
- Full Text :
- https://doi.org/10.21873/anticanres.15641