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Diagnosis and Evaluation of Hypogonadism.

Authors :
Matsumoto AM
Source :
Endocrinology and metabolism clinics of North America [Endocrinol Metab Clin North Am] 2022 Mar; Vol. 51 (1), pp. 47-62. Date of Electronic Publication: 2022 Feb 08.
Publication Year :
2022

Abstract

A systematic approach to diagnose hypogonadism initially establishes the presence of symptoms/signs of testosterone deficiency, considers other potential causes of manifestations, and excludes conditions that transiently suppress testosterone. Hypogonadism is confirmed by measuring fasting serum total testosterone in the morning on at least 2 separate days, or free testosterone by equilibrium dialysis or calculated free testosterone in men with conditions that alter sex hormone-binding globulin or serum total testosterone near lower limit of normal. To guide management, further evaluation is performed to identify the specific cause of hypogonadism and whether it is potentially reversible or an irreversible pathologic disorder.<br />Competing Interests: Disclosure No disclosures.<br /> (Copyright © 2021 Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1558-4410
Volume :
51
Issue :
1
Database :
MEDLINE
Journal :
Endocrinology and metabolism clinics of North America
Publication Type :
Academic Journal
Accession number :
35216720
Full Text :
https://doi.org/10.1016/j.ecl.2021.11.001