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Circulation of an Artemisinin-Resistant Malaria Lineage in a Traveler Returning from East Africa to France.
- Source :
-
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2022 Sep 30; Vol. 75 (7), pp. 1242-1244. - Publication Year :
- 2022
-
Abstract
- A returned traveler to Uganda presented with a Plasmodium falciparum kelch13 A675V mutant infection that exhibited delayed clearance under artesunate therapy. Parasites were genetically related to recently reported Ugandan artemisinin-resistant A675V parasites. Adequate malaria prevention measures and clinical and genotypic surveillance are important tools to avoid and track artemisinin resistance.<br />Competing Interests: Potential conflicts of interest. All authors: No reported conflicts. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest.<br /> (© The Author(s) 2022. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.)
- Subjects :
- Artesunate therapeutic use
Drug Resistance genetics
Humans
Plasmodium falciparum genetics
Protozoan Proteins
Uganda
Antimalarials pharmacology
Antimalarials therapeutic use
Artemisinins pharmacology
Artemisinins therapeutic use
Malaria, Falciparum drug therapy
Malaria, Falciparum epidemiology
Malaria, Falciparum parasitology
Subjects
Details
- Language :
- English
- ISSN :
- 1537-6591
- Volume :
- 75
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
- Publication Type :
- Academic Journal
- Accession number :
- 35213688
- Full Text :
- https://doi.org/10.1093/cid/ciac162