Gastrointestinal disorder biomarkers.

Authors :: Ranjbar R
Ghasemian M
Maniati M
Khatami SH
Jamali N
Taheri-Anganeh M
Source :: Clinica chimica acta; international journal of clinical chemistry [Clin Chim Acta] 2022 May 01; Vol. 530, pp. 13-26. Date of Electronic Publication: 2022 Feb 19.
Publication Year :: 2022
Abstract: Gastrointestinal (GI) disorders refer to gastrointestinal tract conditions, ranging from dyspepsia to inflammatory bowel diseases (IBDs) and malignant tumors. Biomarkers, which are assessable indicators of the presence or severity of the disorders, are indispensable agents to diagnose GI conditions. Diagnostic biomarkers, including serological biomarkers, antibodies, immunological biomarkers, fecal biomarkers, and genetic biomarkers (Non-encoding RNAs), are investigated and categorized in this review. Furthermore, we have discussed the essential biological functions and diagnostic roles and the advantages and disadvantages of these biomarkers, besides novel genetic biomarkers such as miRNA-146a and their role in GI diseases.<br /> (Copyright © 2022 Elsevier B.V. All rights reserved.)

Subjects :: Biomarkers
Feces
Humans
Gastrointestinal Diseases diagnosis
Inflammatory Bowel Diseases diagnosis

Language :: English
ISSN :: 1873-3492
Volume :: 530
Database :: MEDLINE
Journal :: Clinica chimica acta; international journal of clinical chemistry
Publication Type :: Academic Journal
Accession number :: 35192856
Full Text :: https://doi.org/10.1016/j.cca.2022.02.013