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[Histopathological evaluation of nonalcoholic fatty liver disease : Automated evaluation of liver biopsies].

Authors :
Abedin N
Tannapfel A
Wild PJ
Tischoff I
Source :
Der Pathologe [Pathologe] 2022 Mar; Vol. 43 (2), pp. 157-166. Date of Electronic Publication: 2022 Feb 16.
Publication Year :
2022

Abstract

Nonalcoholic fatty liver disease (NAFLD) is one of the most frequent chronic liver diseases with a rising incidence in industrial countries. This is accompanied by an increased prevalence for NAFLD-associated liver cirrhosis and an increased risk for developing hepatocellular carcinoma. The current gold standard in the diagnostics is a liver biopsy. The histopathological evaluation is performed through semiquantitative scoring. To optimize the standardization and quantification of the existing scoring systems, in the coming years procedures with artificial intelligence, such as deep learning models could be used. Fields of application could be the supplementation of conventional histopathological diagnostics, the identification of new predictive parameters for estimating the prognosis and the prediction of a possible response to treatment.<br /> (© 2022. The Author(s), under exclusive licence to Springer Medizin Verlag GmbH, ein Teil von Springer Nature.)

Details

Language :
German
ISSN :
1432-1963
Volume :
43
Issue :
2
Database :
MEDLINE
Journal :
Der Pathologe
Publication Type :
Academic Journal
Accession number :
35171314
Full Text :
https://doi.org/10.1007/s00292-022-01052-w