Low-grade diffusely infiltrative tumour (LGDIT), SMARCB1-mutant: A clinical and histopathological distinct entity showing epigenetic similarity with ATRT-MYC.

Authors :: Hasselblatt M
Thomas C
Federico A
Bens S
Hellström M
Casar-Borota O
Kordes U
Neumann JE
Dottermusch M
Rodriguez FJ
Lo AC
Cheng S
Hendson G
Hukin J
Hartmann C
Koch A
Capper D
Siebert R
Paulus W
Nemes K
Johann PD
Frühwald MC
Kool M
Source :: Neuropathology and applied neurobiology [Neuropathol Appl Neurobiol] 2022 Jun; Vol. 48 (4), pp. e12797. Date of Electronic Publication: 2022 Feb 18.
Publication Year :: 2022
Abstract: Low-grade diffusely infiltrative tumour (LGDIT), SMARCB1-mutant, is a histopathological distinct low-grade lesion encountered in older children and young adults that shows epigenetic similarity with ATRT-MYC and has the potential for malignant progression.<br /> (© 2022 The Authors. Neuropathology and Applied Neurobiology published by John Wiley & Sons Ltd on behalf of British Neuropathological Society.)

Subjects :: Child
Epigenesis, Genetic
Humans
SMARCB1 Protein genetics
Young Adult
Rhabdoid Tumor pathology
Teratoma

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