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Low waist circumference prior to percutaneous coronary intervention predict the risk for end-stage renal disease: a nationwide Korean population based-cohort study.
- Source :
-
The Korean journal of internal medicine [Korean J Intern Med] 2022 May; Vol. 37 (3), pp. 639-652. Date of Electronic Publication: 2022 Feb 11. - Publication Year :
- 2022
-
Abstract
- Background/aims: The obesity paradox has been known in end-stage renal disease (ESRD). However, the effect of body mass index (BMI) or waist circumference (WC) prior to percutaneous coronary intervention (PCI) on the development of ESRD is not clear.<br />Methods: Using nationally representative data from the Korean National Health Insurance System, we enrolled 140,164 subjects without ESRD at enrolment who underwent PCI between 2010 and 2015, and were followed-up until 2017. Patients were stratified into five levels based on their baseline BMI and six levels based on their WC with 5-cm increments. BMI and WC were measured at least 2 years prior to PCI. The primary outcome was the development of ESRD.<br />Results: During a median follow-up of 5.4 years, 2,082 (1.49%) participants developed ESRD. The underweight group (hazard ratio [HR], 1.331; 95% confidence interval [CI], 0.955 to 1.856) and low WC (< 80/< 75) (HR, 1.589; 95% CI, 1.379 to 1.831) showed the highest ESRD risk and the BMI 25 to 30 group showed the lowest ESRD risk (HR, 0.604; 95% CI, 0542 to 0.673) in all participants after adjusting for all covariates. In the subgroup analysis for diabetes mellitus (DM) duration, WC < 85/80 cm (men/women) increased ESRD risk in only the DM group (DM < 5 years and DM ≥ 5 years) compared to the reference group (85-90/80-85 of WC), but not the normal or impaired fasting glucose group.<br />Conclusion: Low WC prior to PCI showed an increased ESRD risk in patients with DM undergoing PCI as compared to those without DM.
Details
- Language :
- English
- ISSN :
- 2005-6648
- Volume :
- 37
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- The Korean journal of internal medicine
- Publication Type :
- Academic Journal
- Accession number :
- 35143719
- Full Text :
- https://doi.org/10.3904/kjim.2021.313