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Prolonged SARS-CoV-2 RNA shedding in a young man recovering from traumatic pneumothorax.
- Source :
-
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde [S Afr Med J] 2022 Feb 01; Vol. 112 (2), pp. 13499. Date of Electronic Publication: 2022 Feb 01. - Publication Year :
- 2022
-
Abstract
- We describe a case of prolonged SARS-CoV-2 RNA shedding in an HIV-negative 21-year-old man recovering from abdominal and thoracic trauma. Nasopharyngeal (NP) swabs collected at 12 time points over a 95-day span all tested positive for SARS-CoV-2 by reverse transcription polymerase chain reaction (RT-PCR). Genotyping revealed canonical beta-variant E484K and N501Y mutations at earlier time points. Human rhinovirus, coronavirus NL63 and respiratory syncytial virus B were detected at different time points by RT-PCR. Full blood analysis at time point 9 (day 82) showed leukopenia with lymphocytosis. The patient's NP swab tested negative for SARS-CoV-2 by RT-PCR 101 days after the first positive test. The prolonged duration of SARS-CoV-2 RNA shedding in the context of trauma presented here is unique and has important implications for COVID-19 diagnosis, management and policy guidelines.
Details
- Language :
- English
- ISSN :
- 2078-5135
- Volume :
- 112
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde
- Publication Type :
- Academic Journal
- Accession number :
- 35139987