Back to Search
Start Over
Modalities and preferred routes of geographic spread of cholera from endemic areas in eastern Democratic Republic of the Congo.
- Source :
-
PloS one [PLoS One] 2022 Feb 07; Vol. 17 (2), pp. e0263160. Date of Electronic Publication: 2022 Feb 07 (Print Publication: 2022). - Publication Year :
- 2022
-
Abstract
- Cholera is endemic along the Great Lakes Region, in eastern Democratic Republic of the Congo (DRC). From these endemic areas, also under perpetual conflicts, outbreaks spread to other areas. However, the main routes of propagation remain unclear. This research aimed to explore the modalities and likely main routes of geographic spread of cholera from endemic areas in eastern DRC. We used historical reconstruction of major outbreak expansions of cholera since its introduction in eastern DRC, maps of distribution and spatiotemporal cluster detection analyses of cholera data from passive surveillance (2000-2017) to describe the spread dynamics of cholera from eastern DRC. Four modalities of geographic spread and their likely main routes from the source areas of epidemics to other areas were identified: in endemic eastern provinces, and in non-endemic provinces of eastern, central and western DRC. Using non-parametric statistics, we found that the higher the number of conflict events reported in eastern DRC, the greater the geographic spread of cholera across the country. The present study revealed that the dynamics of the spread of cholera follow a fairly well-defined spatial logic and can therefore be predicted.<br />Competing Interests: The authors have declared that no competing interests exist.
- Subjects :
- Democratic Republic of the Congo epidemiology
Disease Outbreaks statistics & numerical data
Endemic Diseases statistics & numerical data
Epidemics statistics & numerical data
History, 20th Century
History, 21st Century
Humans
Lakes
Morbidity
Mortality
Spatio-Temporal Analysis
Cholera epidemiology
Cholera transmission
Subjects
Details
- Language :
- English
- ISSN :
- 1932-6203
- Volume :
- 17
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- PloS one
- Publication Type :
- Academic Journal
- Accession number :
- 35130304
- Full Text :
- https://doi.org/10.1371/journal.pone.0263160