Back to Search
Start Over
Antibacterial Activity and Epigenetic Remodeling of Essential Oils from Calabrian Aromatic Plants.
- Source :
-
Nutrients [Nutrients] 2022 Jan 17; Vol. 14 (2). Date of Electronic Publication: 2022 Jan 17. - Publication Year :
- 2022
-
Abstract
- Natural compounds have historically had a wide application in nutrition. Recently, a fundamental role has been identified for essential oils extracted from aromatic plants for their nutritional, antimicrobial, and antioxidant properties, and as food preservatives. In the present study, essential oils (EOs) from ten aromatic plants grown in Calabria (Italy), used routinely to impart aroma and taste to food, were evaluated for their antibacterial activity. This activity was investigated against Escherichia coli strain JM109, and its derived antibiotic-resistant cells selected by growing the strain at low concentrations of ampicillin, ciprofloxacin, and gentamicin by measuring the minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC). Although all the essential oils showed bactericidal activity, those from Clinopodium nepeta , Origanum vulgare , and Foeniculum vulgare displayed the greatest inhibitory effects on the bacterial growth of all cell lines. It is plausible that the antibacterial activity is mediated by epigenetic modifications since the tested essential oils induce methylation both at adenine and cytosine residues in the genomes of most cell lines. This study contributes to a further characterization of the properties of essential oils by shedding new light on the molecular mechanisms that mediate these properties.
- Subjects :
- DNA Methylation
Drug Resistance, Bacterial drug effects
Escherichia coli drug effects
Foeniculum chemistry
Foeniculum genetics
Italy
Lamiaceae chemistry
Lamiaceae genetics
Microbial Sensitivity Tests
Odorants
Oils, Volatile chemistry
Origanum chemistry
Origanum genetics
Plant Oils chemistry
Plants chemistry
Taste
Anti-Bacterial Agents pharmacology
Epigenesis, Genetic
Oils, Volatile pharmacology
Plant Oils pharmacology
Subjects
Details
- Language :
- English
- ISSN :
- 2072-6643
- Volume :
- 14
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Nutrients
- Publication Type :
- Academic Journal
- Accession number :
- 35057572
- Full Text :
- https://doi.org/10.3390/nu14020391