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Five new Erythrina alkaloids from the stems of Erythrina corallodendron .

Authors :
Cai YS
Li YT
Fu J
Chen ZC
Wang Y
Li Y
Yu SS
Source :
Journal of Asian natural products research [J Asian Nat Prod Res] 2022 May; Vol. 24 (5), pp. 457-467. Date of Electronic Publication: 2022 Jan 13.
Publication Year :
2022

Abstract

Five new Erythrina alkaloids and five known E. alkaloids were isolated from a 95% ethanol extract of the stems of Erythrina corallodendron L. Their chemical structures were elucidated by UV, IR, HRESIMS, NMR and X-ray. Furthermore, the analgesic activities of E. alkaloids 1 , 2 and 6 were evaluated by using an acetic acid-induced writhing test in mice, and their writhing inhibition rates were 67.9%, 64.6% and 70.3% at doses of 20 mg/kg, respectively.

Details

Language :
English
ISSN :
1477-2213
Volume :
24
Issue :
5
Database :
MEDLINE
Journal :
Journal of Asian natural products research
Publication Type :
Academic Journal
Accession number :
35023423
Full Text :
https://doi.org/10.1080/10286020.2021.2025050