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Titanium-Based Alloy Surface Modification with TiO 2 and Poly(sodium 4-styrenesulfonate) Multilayers for Dental Implants.
- Source :
-
ACS applied bio materials [ACS Appl Bio Mater] 2021 Apr 19; Vol. 4 (4), pp. 3055-3066. Date of Electronic Publication: 2021 Mar 11. - Publication Year :
- 2021
-
Abstract
- Implant placement is an important repair method in dentistry and orthopedics. Increasing efforts have focused on optimizing the biocompatibility and osseointegration properties of titanium (Ti) and Ti-based alloys. In this work, Ti-based alloys were modified by the layer-by-layer (LbL) technique, which is a simple and versatile method for surface modification. The morphology and chemical structure of LbL films of poly(sodium 4-styrenesulfonate) (PSS) and Ti dioxide (TiO <subscript>2</subscript> ) nanoparticles were first characterized employing ultraviolet-visible and Fourier-transform infrared spectroscopies as well as atomic force microscopy for further application in Ti-based alloy implants. The changes provoked by the LbL PSS/TiO <subscript>2</subscript> film on the Ti-based alloy surfaces were then investigated by scanning electron microscopy and micro-Raman techniques. Finally, in vivo tests (immunolabeling and biomechanical analysis) performed with screw implants in rats suggested that PSS/TiO <subscript>2</subscript> multilayers promote changes in both topography and chemical surface properties of the screw, providing beneficial effects for osteoblast activity. This simple and relatively low-cost growth process can open up possibilities to improve dental implants and, probably, bone implants in general.
Details
- Language :
- English
- ISSN :
- 2576-6422
- Volume :
- 4
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- ACS applied bio materials
- Publication Type :
- Academic Journal
- Accession number :
- 35014394
- Full Text :
- https://doi.org/10.1021/acsabm.0c01348