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Macrophage Polarity and Disease Control.
- Source :
-
International journal of molecular sciences [Int J Mol Sci] 2021 Dec 23; Vol. 23 (1). Date of Electronic Publication: 2021 Dec 23. - Publication Year :
- 2021
-
Abstract
- Macrophages are present in most human tissues and have very diverse functions. Activated macrophages are usually divided into two phenotypes, M1 macrophages and M2 macrophages, which are altered by various factors such as microorganisms, tissue microenvironment, and cytokine signals. Macrophage polarity is very important for infections, inflammatory diseases, and malignancies; its management can be key in the prevention and treatment of diseases. In this review, we assess the current state of knowledge on macrophage polarity and report on its prospects as a therapeutic target.
Details
- Language :
- English
- ISSN :
- 1422-0067
- Volume :
- 23
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- International journal of molecular sciences
- Publication Type :
- Academic Journal
- Accession number :
- 35008577
- Full Text :
- https://doi.org/10.3390/ijms23010144