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Outcomes of patients with double/triple expressor diffuse large B-cell lymphoma (DLBCL) treated with R-DA-EPOCH/R-CHOP: A single-center experience.

Authors :
Devi K
Shaikh MU
Ali NB
Adil SN
Khan M
Soomar SM
Source :
Leukemia research reports [Leuk Res Rep] 2021 Nov 29; Vol. 16, pp. 100284. Date of Electronic Publication: 2021 Nov 29 (Print Publication: 2021).
Publication Year :
2021

Abstract

In Pakistan 76.4% of all NHLs to be diagnosed as DLBCLs. The survival of R-CHOP is better compared to the DA-REPOCH treatment regimen. A prospective follow-up study was conducted with 113 patients to study the outcomes of treatment. Multivariable cox-proportional hazard model was used to estimate the hazard ratios in patients receiving these treatment regimens considering p-value ≤0.05 significant. The survival rate among double/triple expressor lymphoma patients received R-DA-EPOCH was 82.8%, and 83.3% received R-CHOP. For double/triple expressor lymphoma patients received R-DA-EPOCH. The findings of our study demonstrated that the survival rate in both R-CHOP and R-DA-EPOCH is mostly similar.<br />Competing Interests: The authors declare no competing interest<br /> (© 2021 Published by Elsevier Ltd.)

Details

Language :
English
ISSN :
2213-0489
Volume :
16
Database :
MEDLINE
Journal :
Leukemia research reports
Publication Type :
Academic Journal
Accession number :
34926144
Full Text :
https://doi.org/10.1016/j.lrr.2021.100284