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Assessment of Calibration Models for Cuff-Less Blood Pressure Measurement After One Year of Aging.

Authors :
Yavarimanesh M
Block RC
Natarajan K
Mestha LK
Inan OT
Hahn JO
Mukkamala R
Source :
IEEE transactions on bio-medical engineering [IEEE Trans Biomed Eng] 2022 Jun; Vol. 69 (6), pp. 2087-2093. Date of Electronic Publication: 2022 May 19.
Publication Year :
2022

Abstract

Objective: Many calibration models for cuff-less blood pressure (BP) measurement must be periodically updated with cuff BP values to account for vascular aging. However, the time period required for these "cuff re-calibrations" is largely unknown. The impact of one year of aging on several calibration models was assessed.<br />Methods: Ten humans (6 males, 57±18 years, 3 hypertensives) were studied during multiple recording sessions that occurred one year apart. In each session, electrocardiography (ECG), ear photoplethysmography (PPG), finger PPG, and toe PPG waveforms and manual cuff BP were recorded before and after slow breathing, mental arithmetic, cold pressor, and nitroglycerin. Linear models based on each PPG waveform, which were previously shown to offer value in predicting the intervention-induced BP changes in a larger subject cohort, were employed. The model coefficients were determined for each subject via one session, and the fully-defined, subject-specific calibration models were then evaluated in the corresponding subjects via the session one year later.<br />Results: Only a linear model relating toe pulse arrival time (PAT) - time delay between ECG R-wave and toe PPG foot - to systolic BP (SBP) remained useful. After the year, this model changed little on average (root-mean-squared-error (RMSE) = 1.5 mmHg) and predicted the cuff BP values better than the average of the initial cuff BP values of the subject (RMSE = 9.6±0.8 mmHg vs. 12.7±1.0 mmHg; p < 0.05).<br />Conclusion: These results suggest annual cuff recalibrations for the toe PAT-SBP model.<br />Significance: Toe PAT may offer a practical recalibration period that fosters user adherence.

Details

Language :
English
ISSN :
1558-2531
Volume :
69
Issue :
6
Database :
MEDLINE
Journal :
IEEE transactions on bio-medical engineering
Publication Type :
Academic Journal
Accession number :
34919515
Full Text :
https://doi.org/10.1109/TBME.2021.3136492