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A case of recurrent steroid-dependent severe type 2 lepra reaction treated successfully with colchicine.

Authors :
Sachdeva S
Sinha S
Sardana K
Source :
International journal of mycobacteriology [Int J Mycobacteriol] 2021 Oct-Dec; Vol. 10 (4), pp. 472-474.
Publication Year :
2021

Abstract

Type 2 lepra reaction (or erythema nodosum leprosum [ENL]) is an immune complex-mediated reaction which has been reported to occur for up to 8 years after successful completion of multibacillary multidrug therapy. The management of ENL is a challenge with the patient often becoming steroid dependent; predisposing to recurrent episodes in 39%-77% of cases on attempted steroid withdrawal. Here, we present a case of recalcitrant recurrent type 2 reaction which responded promptly to treatment with colchicine.<br />Competing Interests: None

Details

Language :
English
ISSN :
2212-554X
Volume :
10
Issue :
4
Database :
MEDLINE
Journal :
International journal of mycobacteriology
Publication Type :
Report
Accession number :
34916470
Full Text :
https://doi.org/10.4103/ijmy.ijmy_164_21