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Autoantibodies and SARS-CoV2 infection: The spectrum from association to clinical implication: Report of the 15th Dresden Symposium on Autoantibodies.

Authors :
Damoiseaux J
Dotan A
Fritzler MJ
Bogdanos DP
Meroni PL
Roggenbuck D
Goldman M
Landegren N
Bastard P
Shoenfeld Y
Conrad K
Source :
Autoimmunity reviews [Autoimmun Rev] 2022 Mar; Vol. 21 (3), pp. 103012. Date of Electronic Publication: 2021 Dec 09.
Publication Year :
2022

Abstract

The relation between infections and autoimmune diseases has been extensively investigated. Multiple studies suggest a causal relation between these two entities with molecular mimicry, hyperstimulation and dysregulation of the immune system as plausible mechanisms. The recent pandemic with a new virus, i.e., SARS-CoV-2, has resulted in numerous studies addressing the potential of this virus to induce autoimmunity and, eventually, autoimmune disease. In addition, it has also revealed that pre-existing auto-immunity (auto-Abs neutralizing type I IFNs) could cause life-threatening disease. Therefore, the topic of the 15th Dresden Symposium on Autoantibodies was focused on autoimmunity in the SARS-CoV-2 era. This report is a collection and distillation of the topics presented at this meeting.<br /> (Copyright © 2021 The Author(s). Published by Elsevier B.V. All rights reserved.)

Details

Language :
English
ISSN :
1873-0183
Volume :
21
Issue :
3
Database :
MEDLINE
Journal :
Autoimmunity reviews
Publication Type :
Academic Journal
Accession number :
34896650
Full Text :
https://doi.org/10.1016/j.autrev.2021.103012