Pineal Yolk Sac Tumor Producing α-Fetoprotein Detected by 68Ga-FAPI PET/MRI.

Authors :: Dai Y
Pang Y
Bao W
Cheng Y
Chen H
Source :: Clinical nuclear medicine [Clin Nucl Med] 2022 Jan 01; Vol. 47 (1), pp. 90-92.
Publication Year :: 2022
Abstract: Abstract: Pineal yolk sac tumors (YSTs) are a rare type of extragonadal YST. They make up a small fraction of all intracranial germ cell tumors and an even small fraction of pineal masses overall. This study reported a case of pineal YST with α-fetoprotein production revealed by 18F-FDG and 68Ga-FAPI PET/MRI. In the PET images, 68Ga-FAPI showed a far better tumor-to-background ratio than 18F-FDG in the pineal YST because there is little 68Ga-FAPI uptake in the brain. This case indicates that 68Ga-FAPI PET/MRI may be a useful tool for evaluating intracranial YST and other types of tumors in central nervous system.<br />Competing Interests: Conflicts of interest and sources of funding: none declared.<br /> (Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.)