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Diagnostic Utility of CDC DPDx for an Atypical Presentation of Infectious Crystalline Keratopathy-Like Infiltrate Secondary to Microsporidia.
- Source :
-
Cornea [Cornea] 2022 Jan 01; Vol. 41 (1), pp. 109-112. - Publication Year :
- 2022
-
Abstract
- Purpose: To report a case of atypical infectious crystalline keratopathy-like stromal infection secondary to microsporidia wherein diagnosis of the causative organism was aided by use of the Center for Disease Control (CDC) DPDx program.<br />Methods: We report the case of a 73-year-old woman who presented with atypical infectious crystalline keratopathy-like corneal infection without previous surgical history.<br />Results: The patient had previously been treated for recalcitrant corneal infection with topical antibiotics and steroids at an outside provider before referral. Further treatment with topical fortified antibiotics failed to improve the infection. Corneal biopsy was performed and sent to the CDC DPDx for diagnostic confirmation for presumptive microsporidia. The patient underwent therapeutic penetrating keratoplasty without recurrence of ocular infection.<br />Conclusions: Utilization of the DPDx resource may help guide appropriate and timely diagnosis and management strategies in atypical presentations of infectious keratitis.<br />Competing Interests: The authors have no funding or conflicts of interest to disclose.<br /> (Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.)
- Subjects :
- Aged
Cornea microbiology
Eye Infections, Bacterial microbiology
Female
Humans
Keratitis microbiology
Microsporidiosis microbiology
United States
Centers for Disease Control and Prevention, U.S. statistics & numerical data
Cornea pathology
Eye Infections, Bacterial diagnosis
Keratitis diagnosis
Microsporidia isolation & purification
Microsporidiosis diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 1536-4798
- Volume :
- 41
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Cornea
- Publication Type :
- Academic Journal
- Accession number :
- 34870625
- Full Text :
- https://doi.org/10.1097/ICO.0000000000002715