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Atypical preeclampsia without underlying disease and elevated sFlt-1/PlGF ratio.
- Source :
-
The journal of obstetrics and gynaecology research [J Obstet Gynaecol Res] 2022 Feb; Vol. 48 (2), pp. 471-476. Date of Electronic Publication: 2021 Dec 01. - Publication Year :
- 2022
-
Abstract
- Atypical preeclampsia before 20 weeks of gestation without an underlying disease is very rare; however, the soluble Fms-like tyrosine kinase 1/placental growth factor (sFlt-1/PlGF) ratios remain unknown. Four pregnant women with no underlying disease, except for a history of childhood IgA vasculitis, developed preeclampsia at 13, 14, 17, and 18 weeks of gestation with sFlt-1/PlGF ratios of 1589, 1183, 500, and 1460 pg/mL, respectively. Their pregnancies were terminated, and they delivered within 2 weeks. All previously abnormal clinical findings normalized within 3 months. The sFlt-1/PlGF ratios were elevated in the four patients with atypical preeclampsia without underlying disease before 20 weeks of gestation. A high sFlt-1/PlGF ratio may be indicative of preeclampsia when no underlying disease is present in pregnancies of less than 20 weeks of gestation.<br /> (© 2021 Japan Society of Obstetrics and Gynecology.)
Details
- Language :
- English
- ISSN :
- 1447-0756
- Volume :
- 48
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- The journal of obstetrics and gynaecology research
- Publication Type :
- Report
- Accession number :
- 34852396
- Full Text :
- https://doi.org/10.1111/jog.15117