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Euphohyrisnoids A and B, Two Highly Rearranged Lathyrane Diterpenoids from Euphorbia lathyris .
- Source :
-
Organic letters [Org Lett] 2021 Dec 17; Vol. 23 (24), pp. 9602-9605. Date of Electronic Publication: 2021 Nov 24. - Publication Year :
- 2021
-
Abstract
- Euphohyrisnoids A ( 1 ) and B ( 2 ), two highly rearranged lathyrane diterpenoids featuring a unique tetracyclo[10.2.2.0 <superscript>1,10</superscript> .0 <superscript>3,7</superscript> ]cetane and tricyclo[8.4.1.0 <superscript>3,7</superscript> ]pentadecane skeleton, respectively, were isolated from the seeds of Euphorbia lathyris . Their structures were determined by detailed spectroscopic analysis and were further confirmed by single-crystal X-ray diffraction. 1 significantly inhibited adipogenesis in 3T3-L1 adipocytes by retarding cell differentiation at the early stage.
Details
- Language :
- English
- ISSN :
- 1523-7052
- Volume :
- 23
- Issue :
- 24
- Database :
- MEDLINE
- Journal :
- Organic letters
- Publication Type :
- Academic Journal
- Accession number :
- 34816718
- Full Text :
- https://doi.org/10.1021/acs.orglett.1c03812