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The genome sequence of the Australian filarial nematode, Cercopithifilaria johnstoni .

Authors :
McCann K
Grant W
Doyle SR
Source :
Wellcome open research [Wellcome Open Res] 2021 Dec 03; Vol. 6, pp. 259. Date of Electronic Publication: 2021 Dec 03 (Print Publication: 2021).
Publication Year :
2021

Abstract

We present a genome assembly and annotation of an individual female Cercopithifilaria johnstoni , a parasitic filarial nematode that is transmitted by hard ticks (Ixodidae) to infect a broad range of native Australian murid and marsupial hosts. The genome sequence is 76.9 Mbp in length, and although in draft form (N50 = 99 kbp, N50[n] = 232), is largely complete based on universally conserved orthologs (BUSCOs; genome = 94.9%, protein = 96.5%) and relative to other related filarial species. These data represent the first genomic resources for the genus Cercopithifilaria , a group of parasites with a broad host range, and form the basis for comparative analysis with the human-infective parasite, Onchocerca volvulus , both of which are responsible for similar eye and skin pathologies in their respective hosts.<br />Competing Interests: No competing interests were disclosed.<br /> (Copyright: © 2021 McCann K et al.)

Details

Language :
English
ISSN :
2398-502X
Volume :
6
Database :
MEDLINE
Journal :
Wellcome open research
Publication Type :
Academic Journal
Accession number :
34796277.2
Full Text :
https://doi.org/10.12688/wellcomeopenres.17258.2