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A Review of Platelet-Activating Factor As a Potential Contributor to Morbidity and Mortality Associated with Severe COVID-19.
- Source :
-
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis [Clin Appl Thromb Hemost] 2021 Jan-Dec; Vol. 27, pp. 10760296211051764. - Publication Year :
- 2021
-
Abstract
- The precise mechanisms of pathology in severe COVID-19 remains elusive. Current evidence suggests that inflammatory mediators are responsible for the manifestation of clinical symptoms that precedes a fatal response to infection. This review examines the nature of platelet activating factor and emphasizes the similarities between the physiological effects of platelet activating factor and the clinical complications of severe COVID-19.
- Subjects :
- Animals
COVID-19 complications
COVID-19 mortality
COVID-19 pathology
Humans
Inflammation complications
Inflammation metabolism
Inflammation mortality
Inflammation pathology
Multiple Organ Failure complications
Multiple Organ Failure metabolism
Multiple Organ Failure mortality
Multiple Organ Failure pathology
Respiratory Distress Syndrome complications
Respiratory Distress Syndrome metabolism
Respiratory Distress Syndrome mortality
Respiratory Distress Syndrome pathology
SARS-CoV-2 physiology
Severity of Illness Index
Thrombosis complications
Thrombosis metabolism
Thrombosis mortality
Thrombosis pathology
COVID-19 metabolism
Platelet Activating Factor metabolism
Subjects
Details
- Language :
- English
- ISSN :
- 1938-2723
- Volume :
- 27
- Database :
- MEDLINE
- Journal :
- Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
- Publication Type :
- Academic Journal
- Accession number :
- 34755565
- Full Text :
- https://doi.org/10.1177/10760296211051764