Back to Search
Start Over
Sugary drink consumption and risk of kidney and bladder cancer in Japanese adults.
- Source :
-
Scientific reports [Sci Rep] 2021 Nov 04; Vol. 11 (1), pp. 21701. Date of Electronic Publication: 2021 Nov 04. - Publication Year :
- 2021
-
Abstract
- Globally, sugary drinks are widely consumed, however, few epidemiologic studies have investigated the association between sugary drink consumption and risk of kidney and bladder cancer. We examined the association of sugary drinks with risk of kidney and bladder cancer in 73,024 participants from the Japan Public Health Center-based Prospective Study who reported no history of cancer. Sugary drink consumption was assessed using a validated food frequency questionnaire at study baseline (1995-1999). Individuals were followed to December 31, 2013. Multivariable Cox proportional hazards regression models were used to calculate hazard ratios (HR) and 95% confidence intervals (CIs). During 1,069,815 person years of follow-up, 169 kidney cancer and 297 bladder cancer cases were documented. After adjusting for potential confounders, no greater risk of kidney and bladder cancer was observed. However, sugary drink consumption was positively associated with the risk of kidney cancer (HR for 100 ml/day increase in consumption was 1.11 [95% CI 1.01-1.22]) and bladder cancer (HR for 100 ml/d increase in consumption was 1.11 [95% CI 1.01-1.22]) among women after exclusion of cases diagnosed in the first three years of follow-up. In this large prospective cohort, consumption of sugary drinks was significantly associated with a small increase in hazard ratio for kidney and bladder cancer among women after exclusion of cases diagnosed within the first three years.<br /> (© 2021. The Author(s).)
- Subjects :
- Adult
Beverages
Cohort Studies
Dietary Supplements
Drinking Behavior
Female
Fruit and Vegetable Juices
Humans
Japan epidemiology
Kidney pathology
Kidney Neoplasms epidemiology
Male
Middle Aged
Proportional Hazards Models
Prospective Studies
Risk Factors
Urinary Bladder pathology
Urinary Bladder Neoplasms epidemiology
Kidney Neoplasms etiology
Sugar-Sweetened Beverages adverse effects
Urinary Bladder Neoplasms etiology
Subjects
Details
- Language :
- English
- ISSN :
- 2045-2322
- Volume :
- 11
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Scientific reports
- Publication Type :
- Academic Journal
- Accession number :
- 34737349
- Full Text :
- https://doi.org/10.1038/s41598-021-01103-x