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Far-advanced Colorectal Liver Metastases Successfully Managed With Modified ALPPS and Radiofrequency Ablation in Combination With Chemotherapy.
- Source :
-
Anticancer research [Anticancer Res] 2021 Nov; Vol. 41 (11), pp. 5855-5861. - Publication Year :
- 2021
-
Abstract
- Background: Large numbers of synchronous colorectal liver metastases are associated with poor prognosis.<br />Case Report: A 47-year-old male patient with rectal cancer and unresectable colorectal liver metastases (over 15 cm in diameter and over 30 metastases) was treated with a multidisciplinary treatment including systemic chemotherapy with mFOLFOX6/panitumumab and surgical therapies (colostomy, modified associating liver partition and portal vein ligation for staged hepatectomy together with radiofrequency ablation). For solitary recurrent colorectal liver metastases, percutaneous radiofrequency ablation with chemoembolization and open radiofrequency ablation in combination with the same systemic chemotherapy was performed. Since the diagnosis 3 years ago, he has been leading a good quality of life, free of any tumor or treatment.<br />Conclusion: For patients with far-advanced but liver-only colorectal liver metastases, surgical therapy, systemic chemotherapy, and interventional treatment can be important for achieving good prognosis.<br /> (Copyright © 2021 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.)
- Subjects :
- Adenocarcinoma diagnostic imaging
Adenocarcinoma secondary
Antineoplastic Combined Chemotherapy Protocols adverse effects
Chemotherapy, Adjuvant
Colostomy
Humans
Ligation
Liver Neoplasms diagnostic imaging
Liver Neoplasms secondary
Male
Middle Aged
Neoplasm Staging
Treatment Outcome
Adenocarcinoma therapy
Antineoplastic Combined Chemotherapy Protocols therapeutic use
Colorectal Neoplasms pathology
Hepatectomy
Liver Neoplasms therapy
Neoadjuvant Therapy
Portal Vein surgery
Radiofrequency Ablation
Subjects
Details
- Language :
- English
- ISSN :
- 1791-7530
- Volume :
- 41
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Anticancer research
- Publication Type :
- Report
- Accession number :
- 34732462
- Full Text :
- https://doi.org/10.21873/anticanres.15405