Autoimmune pulmonary alveolar proteinosis with a history of vaping and vitamin E-positive bronchoalveolar lavage.

Authors :: Chua TH
Takano A
Yao YJ
Chow SY
Devanand A
Tay CK
Source :: Respirology case reports [Respirol Case Rep] 2021 Oct 18; Vol. 9 (11), pp. e0864. Date of Electronic Publication: 2021 Oct 18 (Print Publication: 2021).
Publication Year :: 2021
Abstract: Pulmonary alveolar proteinosis (PAP) can be due to primary autoimmune and secondary causes, including e-cigarette, or vaping, product use-associated lung injury. We present a 33-year-old male presenting with PAP and a history of vaping. Serum anti-granulocyte-macrophage colony-stimulating factor antibodies were present. Vitamin E (VE), but not VE acetate, was detected in bronchoalveolar lavage. This is the first report of potential association between vaping and autoimmune PAP.<br />Competing Interests: None declared.<br /> (© 2021 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology.)

Full Text Access

Tools